BDBM50001266 5,7-DICHLORO-4-HYDROXYQUINOLINE-2-CARBOXYLIC ACID::5,7-Dichloro-4-hydroxy-quinoline-2-carboxylic acid::5,7-Dichloro-4-hydroxy-quinoline-2-carboxylic acid anion::5,7-Dichloro-4-hydroxy-quinoline-2-carboxylic acid(DCKA)::5,7-Dichloro-4-oxo-1,4-dihydro-quinoline-2-carboxylic acid::5,7-dichlorokynurenic acid::CHEMBL50267
SMILES OC(=O)c1cc(O)c2c(Cl)cc(Cl)cc2n1
InChI Key InChIKey=BGKFPRIGXAVYNX-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50001266
Affinity DataKi: 40nMAssay Description:Displacement of [3H]glycine from glycine site on the NMDA receptor.More data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Tested for the ability to displace [3H]-glycine, by greater than 50%, from NMDA receptor of rat cortical membranes at a dose of 10 microMMore data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Ability to displace strychnine-insensitive [3H]-glycine binding to rat cortical membranes.More data for this Ligand-Target Pair
Affinity DataKi: 90nMAssay Description:Binding affinity towards N-methyl-D-aspartate glutamate receptor 1 (high affinity) of rat cortical synaptic membranes by using [3H]-Gly as radioligan...More data for this Ligand-Target Pair
Affinity DataEC50: 330nMAssay Description:Functional antagonism at the N-methyl-D-aspartate glutamate receptor 1 was demonstrated by the ability to inhibit the binding of thechannel-blocking ...More data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Ability of compound to compete with [3H]-glycine for the strychnine-insensitive NMDA receptor glycine binding sites on rat cortical and hippocampusMore data for this Ligand-Target Pair
Affinity DataIC50: 860nMAssay Description:Inhibition of [3H]-MK-801 binding to a N-methyl-D-aspartic acid(NMDA) receptor in glycine-sensitive rat cortical membranes.More data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of specific binding of [3H]-glycine to NMDA receptors, in rat cortical membranes at 32 uM conc.More data for this Ligand-Target Pair