BDBM50012683 3-(1-Hydroxy-naphthalen-2-yl)-acrylic acid ethyl ester::CHEMBL122544

SMILES CCOC(=O)\C=C\c1ccc2ccccc2c1O

InChI Key InChIKey=GKOQVDAGVTZSIE-MDZDMXLPSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50012683   

TargetProstaglandin G/H synthase 1/2(Bos taurus)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50012683(3-(1-Hydroxy-naphthalen-2-yl)-acrylic acid ethyl e...)
Affinity DataIC50:  1.10E+4nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase in BSV cell line.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)TBA
LigandPNGBDBM50012683(3-(1-Hydroxy-naphthalen-2-yl)-acrylic acid ethyl e...)
Affinity DataIC50:  45nMAssay Description:Inhibition of 5-lipoxygenase in Rattus norvegicus Rat basophil leukemia cells (RBL) cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)TBA
LigandPNGBDBM50012683(3-(1-Hydroxy-naphthalen-2-yl)-acrylic acid ethyl e...)
Affinity DataIC50:  45nMAssay Description:Ability to inhibit 5-lipoxygenase by using a crude preparation of the cytosolic enzyme from the rat basophilic leukemia (RBL-1) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed