BDBM50014092 CHEMBL3259830::US9187441, 9l

SMILES CC(C)(C)NC(=O)C(N(Cc1ccc(Cl)cc1)C=O)c1c([nH]c2cc(Cl)ccc12)C(O)=O

InChI Key InChIKey=ZAOJHZGIRKVCBH-UHFFFAOYSA-N

Data  4 KI

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50014092   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Pittsburgh

US Patent
LigandPNGBDBM50014092(CHEMBL3259830 | US9187441, 9l)
Affinity DataKi:  300nM ΔG°:  -8.74kcal/moleT: 2°CAssay Description:Fluorescent polarization experiments were performed as follows. Briefly, the fluorescence polarization experiments were read on an Ultra Evolution 38...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Pittsburgh

US Patent
LigandPNGBDBM50014092(CHEMBL3259830 | US9187441, 9l)
Affinity DataKi:  400nMAssay Description:Displacement of fluorescent P4 peptide from MDM2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Pittsburgh

US Patent
LigandPNGBDBM50014092(CHEMBL3259830 | US9187441, 9l)
Affinity DataKi:  400nM ΔG°:  -8.58kcal/moleT: 2°CAssay Description:Fluorescent polarization experiments were performed as follows. Briefly, the fluorescence polarization experiments were read on an Ultra Evolution 38...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Pittsburgh

US Patent
LigandPNGBDBM50014092(CHEMBL3259830 | US9187441, 9l)
Affinity DataKi:  700nM ΔG°:  -8.25kcal/moleT: 2°CAssay Description:Fluorescent polarization experiments were performed as follows. Briefly, the fluorescence polarization experiments were read on an Ultra Evolution 38...More data for this Ligand-Target Pair