BDBM50016687 2-(4-Benzyloxy-phenyl)-N-hydroxy-N-methyl-acetamide::CHEMBL54453

SMILES CN(O)C(=O)Cc1ccc(OCc2ccccc2)cc1

InChI Key InChIKey=MYMPWMRYZURXNI-UHFFFAOYSA-N

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50016687   

TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50016687(2-(4-Benzyloxy-phenyl)-N-hydroxy-N-methyl-acetamid...)
Affinity DataKi:  1.00E+5nMAssay Description:Activity of the compound to bind against [3H]-LTD4 radioligand in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50016687(2-(4-Benzyloxy-phenyl)-N-hydroxy-N-methyl-acetamid...)
Affinity DataIC50:  100nMAssay Description:In vitro inhibition of rat polymorphonuclear leukocyte 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50016687(2-(4-Benzyloxy-phenyl)-N-hydroxy-N-methyl-acetamid...)
Affinity DataIC50:  9.00E+3nMAssay Description:In vitro inhibitory activity against rat polymorphonuclear leukocyte cyclooxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50016687(2-(4-Benzyloxy-phenyl)-N-hydroxy-N-methyl-acetamid...)
Affinity DataIC50:  200nMAssay Description:Invitro inhibitory activity against rat platelet 12-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50016687(2-(4-Benzyloxy-phenyl)-N-hydroxy-N-methyl-acetamid...)
Affinity DataIC50: <1.00E+4nMAssay Description:Invitro inhibition of polymorphonuclear leukocyte derived human 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rattus norvegicus)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50016687(2-(4-Benzyloxy-phenyl)-N-hydroxy-N-methyl-acetamid...)
Affinity DataIC50:  500nMAssay Description:Invitro inhibition of rat platelet 12-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50016687(2-(4-Benzyloxy-phenyl)-N-hydroxy-N-methyl-acetamid...)
Affinity DataIC50:  300nMAssay Description:Invitro inhibition of polymorphonuclear leukocyte derived human 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed