BDBM50022775 (m-Hydroxyphenyl)trimethylammonium dimethylcarbamate::3-Trimethylammoniumphenyl N,N-dimethylcarbamate::3-[(dimethylcarbamoyl)oxy]-N,N,N-trimethylanilinium::CHEMBL211471::CHEMBL278020::Eustigmin::Eustigmine::NEOSTIGMINE::Neostigmine (2)::Prostigmine::Vagostigmine::m-Trimethylammoniumphenyldimethylcarbamate

SMILES CN(C)C(=O)Oc1cccc(c1)[N+](C)(C)C

InChI Key InChIKey=ALWKGYPQUAPLQC-UHFFFAOYSA-N

Data  3 KI  57 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50022775   

TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University of Life Sciences

LigandPNGBDBM50022775((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Affinity DataIC50:  50nMpH: 8.0 T: 2°CAssay Description:Seven different concentrations of the synthesized compounds in the range 10^−3-10^−9 M were measured at 412 nm. All the assays were under...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University of Life Sciences

LigandPNGBDBM50022775((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Affinity DataIC50:  70nMpH: 8.0 T: 2°CAssay Description:Seven different concentrations of the synthesized compounds in the range 10^−3-10^−9 M were measured at 412 nm. All the assays were under...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
University Of Life Sciences

Curated by ChEMBL
LigandPNGBDBM50022775((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Affinity DataIC50:  70nMAssay Description:Inhibition of equine serum BChE using butylthiocholine iodide as substrate after 10 mins by Ellman methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University of Life Sciences

LigandPNGBDBM50022775((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Affinity DataIC50:  50nMAssay Description:Inhibition of electric eel AChE using acetylcholine iodide as substrate after 10 mins by Ellman methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed