BDBM50028192 (S)-7-(2-hydroxypropyl)-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione::7-(2-Hydroxy-propyl)-1,3-dimethyl-3,7-dihydro-purine-2,6-dione::CHEMBL290644

SMILES C[C@H](O)Cn1cnc2n(C)c(=O)n(C)c(=O)c12

InChI Key InChIKey=KYHQZNGJUGFTGR-LURJTMIESA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50028192   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50028192((S)-7-(2-hydroxypropyl)-1,3-dimethyl-1H-purine-2,6...)
Affinity DataKi:  6.00E+5nMAssay Description:Inhibition of human lung high-affinity cGMP phosphodiesterases (0.5-2 microM/L)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50028192((S)-7-(2-hydroxypropyl)-1,3-dimethyl-1H-purine-2,6...)
Affinity DataKi:  7.00E+5nMAssay Description:Inhibition of human lung low-affinity cGMP phosphodiesterases (10-50 microM/L)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50028192((S)-7-(2-hydroxypropyl)-1,3-dimethyl-1H-purine-2,6...)
Affinity DataKi:  1.20E+6nMAssay Description:Inhibitory activity against catechol O-methyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed