BDBM50029548 2-Amino-6-methyl-5-(pyridin-4-ylsulfanyl)-3,4a,7,7a-tetrahydro-pyrrolo[2,3-d]pyrimidin-4-one::CHEMBL138500

SMILES CC1=NC2N=C(N)NC(=O)C2C1Sc1ccncc1

InChI Key InChIKey=ARYUXYOUOSWLCE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50029548   

TargetDihydrofolate reductase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50029548(2-Amino-6-methyl-5-(pyridin-4-ylsulfanyl)-3,4a,7,7...)
Affinity DataIC50: >6.90E+4nMAssay Description:Inhibitory activity against dihydro folate reductase from Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50029548(2-Amino-6-methyl-5-(pyridin-4-ylsulfanyl)-3,4a,7,7...)
Affinity DataIC50: >6.90E+4nMAssay Description:Inhibitory activity against dihydro folate reductase from Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50029548(2-Amino-6-methyl-5-(pyridin-4-ylsulfanyl)-3,4a,7,7...)
Affinity DataIC50:  340nMAssay Description:Inhibitory activity against thymidylate Synthase from human recombinant sourcesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50029548(2-Amino-6-methyl-5-(pyridin-4-ylsulfanyl)-3,4a,7,7...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibitory activity against thymidylate Synthase from Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed