BDBM50033784 8-ethyl-8-hydroxy-9,12-dioxo-2,3,8,9,12,14-hexahydro-11H-[1,4]dioxino[2,3-g]pyrano[3',4':6,7]indolizino[1,2-b]quinoline-15-carboxylic acid::CHEMBL422922

SMILES CCC1(O)C(=O)OCc2c1cc1-c3nc4cc5OCCOc5cc4c(C(O)=O)c3Cn1c2=O

InChI Key InChIKey=PLIJIBZEBJNLOZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50033784   

TargetDNA topoisomerase 1(Homo sapiens (Human))
Glaxo Research Institute

Curated by ChEMBL
LigandPNGBDBM50033784(8-ethyl-8-hydroxy-9,12-dioxo-2,3,8,9,12,14-hexahyd...)
Affinity DataIC50:  2.41E+4nMAssay Description:Inhibitory concentration of the compound against topoisomerase I obtained from calf thymusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed