BDBM50037354 CHEMBL113905::{2-Oxo-6-phenyl-1-[(3,3,3-trifluoro-1-isopropyl-2-oxo-propylcarbamoyl)-methyl]-1,2-dihydro-pyridin-3-yl}-carbamic acid pyridin-2-ylmethyl ester

SMILES CC(C)C(NC(=O)Cn1c(ccc(NC(=O)OCc2ccccn2)c1=O)-c1ccccc1)C(=O)C(F)(F)F

InChI Key InChIKey=UQFRBUDGHOGQRJ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50037354   

TargetNeutrophil elastase(Human)
Zeneca Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50037354(CHEMBL113905 | {2-Oxo-6-phenyl-1-[(3,3,3-trifluoro...)
Affinity DataKi:  8.80nMAssay Description:Binding affinity against human leukocyte elastase (HLE) enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed