BDBM50049729 CHEMBL292887::[3-(3-Nitro-benzyl)-2,4,5-trioxo-imidazolidin-1-yl]-acetic acid

SMILES OC(=O)CN1C(=O)N(Cc2cccc(c2)[N+]([O-])=O)C(=O)C1=O

InChI Key InChIKey=YREIRIKJAMPPHC-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50049729   

TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Nippon Zoki Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50049729(CHEMBL292887 | [3-(3-Nitro-benzyl)-2,4,5-trioxo-im...)
Affinity DataIC50:  62nMAssay Description:In vitro inhibitory activity of the compound against partially purified rat lens Aldose reductase, for experiment 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Nippon Zoki Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50049729(CHEMBL292887 | [3-(3-Nitro-benzyl)-2,4,5-trioxo-im...)
Affinity DataIC50:  130nMAssay Description:In vitro inhibitory activity of the compound against rat lens Aldose reductase, for experiment 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Nippon Zoki Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50049729(CHEMBL292887 | [3-(3-Nitro-benzyl)-2,4,5-trioxo-im...)
Affinity DataIC50:  62nMAssay Description:Inhibitory activity against rat lens aldose reductase(AR).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Nippon Zoki Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50049729(CHEMBL292887 | [3-(3-Nitro-benzyl)-2,4,5-trioxo-im...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory activity of the compound against rat kidney Aldehyde reductase, for experiment 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Nippon Zoki Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50049729(CHEMBL292887 | [3-(3-Nitro-benzyl)-2,4,5-trioxo-im...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against rat kidney aldehyde reductase (ALR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Nippon Zoki Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50049729(CHEMBL292887 | [3-(3-Nitro-benzyl)-2,4,5-trioxo-im...)
Affinity DataIC50:  1.00E+5nMAssay Description:In vitro inhibitory activity of the compound against rat kidney Aldehyde reductase, for experiment 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed