BDBM50050980 (2S,3S,4R)-4-Benzo[1,3]dioxol-5-yl-1-dipropylcarbamoylmethyl-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid::CHEMBL9139

SMILES CCCN(CCC)C(=O)CN1C[C@H]([C@@H]([C@H]1c1ccc(OC)cc1)C(O)=O)c1ccc2OCOc2c1

InChI Key InChIKey=AEDZVHIKLJEHDR-OUIFVKKZSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50050980   

TargetEndothelin receptor type B(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050980((2S,3S,4R)-4-Benzo[1,3]dioxol-5-yl-1-dipropylcarba...)
Affinity DataIC50:  397nMAssay Description:Radioligand binding selectivity of the compound to human Endothelin B receptor in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Pig)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050980((2S,3S,4R)-4-Benzo[1,3]dioxol-5-yl-1-dipropylcarba...)
Affinity DataIC50:  598nMAssay Description:Inhibitory activity measured against Endothelin B receptor binding to porcine cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050980((2S,3S,4R)-4-Benzo[1,3]dioxol-5-yl-1-dipropylcarba...)
Affinity DataIC50:  0.550nMAssay Description:Radioligand binding selectivity of the compound to human Endothelin A receptor in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050980((2S,3S,4R)-4-Benzo[1,3]dioxol-5-yl-1-dipropylcarba...)
Affinity DataIC50:  1.23nMAssay Description:Inhibitory activity against the Endothelin A receptor of rat MMQ cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed