BDBM50054575 (Z)-2-Cyano-3-cyclopropyl-3-hydroxy-N-pyridin-4-yl-acrylamide::CHEMBL342581

SMILES O=C(Nc1ccncc1)C(C#N)C(=O)C1CC1

InChI Key InChIKey=NDRKRVMCYBMMIG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50054575   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Mouse)
Hoechst Marion Roussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054575BDBM50054575((Z)-2-Cyano-3-cyclopropyl-3-hydroxy-N-pyridin-4-yl...)
Affinity DataIC50: 8.91E+3nMAssay Description:Inhibitory concentration tested on enzyme dihydroorotate dehydrogenase in mouseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
Hoechst Marion Roussel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054575BDBM50054575((Z)-2-Cyano-3-cyclopropyl-3-hydroxy-N-pyridin-4-yl...)
Affinity DataIC50: 1.17E+4nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed