BDBM50054781 CHEMBL3318966

SMILES Clc1ccc(cc1)C1(CC1)c1nnc2c(Oc3ccccc3N3CCOCC3)cccn12

InChI Key InChIKey=UUKVPGQBLMJINN-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50054781   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50054781(CHEMBL3318966)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of human recombinant 11beta-HSD-1 expressed in HEK293 EBNA cells using [3H]-cortisone and NADPH by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50054781(CHEMBL3318966)
Affinity DataEC50:  400nMAssay Description:Activation of PXR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed