BDBM50057005 6-Chloro-3-hydroxy-2-methyl-1-oxo-1,2-dihydro-isoquinoline-4-carboxylic acid (2,4-dichloro-phenyl)-amide::CHEMBL177808

SMILES CN1C(=O)C(C(=O)Nc2ccc(Cl)cc2Cl)c2cc(Cl)ccc2C1=O

InChI Key InChIKey=MWGOPRMXNYOCDI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50057005   

TargetProstaglandin G/H synthase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50057005(6-Chloro-3-hydroxy-2-methyl-1-oxo-1,2-dihydro-isoq...)
Affinity DataIC50:  200nMAssay Description:Concentration of drug that causes a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 2 activity as measured by PGE2 production('+...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50057005(6-Chloro-3-hydroxy-2-methyl-1-oxo-1,2-dihydro-isoq...)
Affinity DataIC50:  600nMAssay Description:Concentration of drug that causes a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 1 activity as measured by PGE2 production('+...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed