BDBM50057521 4-[5-(4-Chloro-phenyl)-4-methanesulfonyl-pyrazol-1-yl]-benzenesulfonamide::CHEMBL281001
SMILES CS(=O)(=O)c1cnn(c1-c1ccc(Cl)cc1)-c1ccc(cc1)S(N)(=O)=O
InChI Key InChIKey=SGVCPVBBMCJFLT-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50057521
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Searle Research and Development
Curated by ChEMBL
Searle Research and Development
Curated by ChEMBL
Affinity DataIC50: 5.20E+4nMAssay Description:In vitro inhibitory concentration required to block recombinant human prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research and Development
Curated by ChEMBL
Searle Research and Development
Curated by ChEMBL
Affinity DataIC50: 1.98E+4nMAssay Description:In vitro inhibitory concentration required to block human recombinant prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
Affinity DataIC50: 5.25E+4nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research and Development
Curated by ChEMBL
Searle Research and Development
Curated by ChEMBL
Affinity DataIC50: 1.98E+4nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair