BDBM50057521 4-[5-(4-Chloro-phenyl)-4-methanesulfonyl-pyrazol-1-yl]-benzenesulfonamide::CHEMBL281001

SMILES CS(=O)(=O)c1cnn(c1-c1ccc(Cl)cc1)-c1ccc(cc1)S(N)(=O)=O

InChI Key InChIKey=SGVCPVBBMCJFLT-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50057521   

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057521(4-[5-(4-Chloro-phenyl)-4-methanesulfonyl-pyrazol-1...)
Affinity DataIC50:  5.20E+4nMAssay Description:In vitro inhibitory concentration required to block recombinant human prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057521(4-[5-(4-Chloro-phenyl)-4-methanesulfonyl-pyrazol-1...)
Affinity DataIC50:  1.98E+4nMAssay Description:In vitro inhibitory concentration required to block human recombinant prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057521(4-[5-(4-Chloro-phenyl)-4-methanesulfonyl-pyrazol-1...)
Affinity DataIC50:  5.25E+4nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057521(4-[5-(4-Chloro-phenyl)-4-methanesulfonyl-pyrazol-1...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057521(4-[5-(4-Chloro-phenyl)-4-methanesulfonyl-pyrazol-1...)
Affinity DataIC50:  1.98E+4nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed