BDBM50067686 5-[1-(3,4-Difluoro-phenyl)-meth-(Z)-ylidene]-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene::CHEMBL342426

SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4O\C(=C/c4ccc(F)c(F)c4)c3c12

InChI Key InChIKey=XGBWGDGYTTWUIM-QRVIBDJDSA-N

Data  3 KI  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50067686   

TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50067686(5-[1-(3,4-Difluoro-phenyl)-meth-(Z)-ylidene]-2,2,4...)
Affinity DataKi:  3.60nMAssay Description:Binding affinity against human progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50067686(5-[1-(3,4-Difluoro-phenyl)-meth-(Z)-ylidene]-2,2,4...)
Affinity DataKi:  237nMAssay Description:Binding affinity against human glucocorticoid receptor expressed in SF-12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50067686(5-[1-(3,4-Difluoro-phenyl)-meth-(Z)-ylidene]-2,2,4...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity against human androgen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50067686(5-[1-(3,4-Difluoro-phenyl)-meth-(Z)-ylidene]-2,2,4...)
Affinity DataEC50:  14.7nMAssay Description:Effective concentration (EC50) against human progesterone receptor expressed in CV-1 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50067686(5-[1-(3,4-Difluoro-phenyl)-meth-(Z)-ylidene]-2,2,4...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity (IC50) against human mineralocorticoid receptor expressed in CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50067686(5-[1-(3,4-Difluoro-phenyl)-meth-(Z)-ylidene]-2,2,4...)
Affinity DataIC50:  916nMAssay Description:Inhibitory activity (IC50) against human androgen receptor expressed in CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50067686(5-[1-(3,4-Difluoro-phenyl)-meth-(Z)-ylidene]-2,2,4...)
Affinity DataIC50:  1.65E+3nMAssay Description:Inhibitory activity (IC50) against human glucocorticoid receptor expressed in CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed