BDBM50071365 5-Cyclopropyl-5H-4,5,6-triaza-dibenzo[a,d]cycloheptene::CHEMBL69855

SMILES C1CC1N1c2ncccc2C=Cc2cccnc12

InChI Key InChIKey=MONPDXUIJPRGMZ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50071365   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071365(5-Cyclopropyl-5H-4,5,6-triaza-dibenzo[a,d]cyclohep...)
Affinity DataIC50:  150nMAssay Description:Compound was tested for inhibitory activity against HIV-1 mutant type reverse transcriptase (K103N)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071365(5-Cyclopropyl-5H-4,5,6-triaza-dibenzo[a,d]cyclohep...)
Affinity DataIC50:  630nMAssay Description:Compound was tested for inhibitory activity against HIV-1 mutant type reverse transcriptase (L1001)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071365(5-Cyclopropyl-5H-4,5,6-triaza-dibenzo[a,d]cyclohep...)
Affinity DataIC50:  20nMAssay Description:Compound was tested for inhibitory activity against HIV-1 wild type reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071365(5-Cyclopropyl-5H-4,5,6-triaza-dibenzo[a,d]cyclohep...)
Affinity DataIC50:  960nMAssay Description:Compound was tested for inhibitory activity against HIV-1 mutant type reverse transcriptase (L1001)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071365(5-Cyclopropyl-5H-4,5,6-triaza-dibenzo[a,d]cyclohep...)
Affinity DataIC50:  10nMAssay Description:Compound was tested for inhibitory activity against HIV-1 mutant type reverse transcriptase (Y181C)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed