BDBM50072083 CHEMBL3407929

SMILES OC(=O)[C@H]1C[C@@H]1C(=O)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=ZBRKMOHDGFGXLN-BQBZGAKWSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50072083   

TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50072083(CHEMBL3407929)
Affinity DataIC50:  20nMAssay Description:Inhibition of KMO (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50072083(CHEMBL3407929)
Affinity DataIC50:  20nMAssay Description:Antagonistic activity of guinea pig Histamine H2 receptor expressed as pA2 at pH 7.0More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetKynurenine 3-monooxygenase(Rattus norvegicus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50072083(CHEMBL3407929)
Affinity DataIC50:  20nMAssay Description:Inhibition of KMO in rat brain homogenates using kynurenine as substrate measured after 5 to 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Rattus norvegicus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50072083(CHEMBL3407929)
Affinity DataIC50:  20nMAssay Description:Inhibition of KMO in rat brain homogenates using kynurenine as substrate measured after 5 to 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed