BDBM50072593 5-(Biphenyl-3-yl-difluoro-methyl)-1-sodium-1H-tetrazole::CHEMBL109530

SMILES FC(F)(c1nn[n-]n1)c1cccc(c1)-c1ccccc1

InChI Key InChIKey=HZTJTZYQBQYIQK-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50072593   

TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50072593(5-(Biphenyl-3-yl-difluoro-methyl)-1-sodium-1H-tetr...)
Affinity DataKi:  9.80E+4nMAssay Description:Inhibitory activity against protein tyrosine phosphatase 1B (PTP1B) using fluorescein diphosphate as substrate at Km concentration (20 uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50072593(5-(Biphenyl-3-yl-difluoro-methyl)-1-sodium-1H-tetr...)
Affinity DataIC50:  1.95E+5nMAssay Description:Inhibitory activity against protein tyrosine phosphatase 1B (PTP1B) using fluorescein diphosphate as substrate at Km concentration (20 uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed