BDBM50077233 CHEMBL443523::N-(4-(3-bromophenylamino) quinazolin-7-yl)acrylamide::N-(4-(3-bromophenylamino)quinazolin-7-yl)acrylamide::N-[4-(3-Bromo-phenylamino)-quinazolin-7-yl]-acrylamide

SMILES Brc1cccc(Nc2ncnc3cc(NC(=O)C=C)ccc23)c1

InChI Key InChIKey=YGFCGWOZJQMOOG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50077233   

TargetEpidermal growth factor receptor(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50077233(CHEMBL443523 | N-(4-(3-bromophenylamino) quinazoli...)
Affinity DataIC50:  14nMAssay Description:Inhibition of EGF-stimulated autophosphorylation of epidermal growth factor receptor (EGFR) in A431 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50077233(CHEMBL443523 | N-(4-(3-bromophenylamino) quinazoli...)
Affinity DataIC50:  73nMAssay Description:Inhibition of heregulin-stimulated autophosphorylation of ERBB2 receptor kinase in MDA-MB-453 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50077233(CHEMBL443523 | N-(4-(3-bromophenylamino) quinazoli...)
Affinity DataIC50:  0.450nMAssay Description:Inhibition of phosphorylation of glutamic acid/tyrosine random copolymer by isolated epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed