BDBM50084649 CHEMBL3114664

SMILES Nc1onc(-c2ccc(Cl)o2)c1-c1ccccc1

InChI Key InChIKey=ABPABQXEIYHSAF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50084649   

TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Universit£

Curated by ChEMBL
LigandPNGBDBM50084649(CHEMBL3114664)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of ovine COX-1 assessed as inhibition of PGH2 production using arachidonic acid as substrate by TMPD oxidation based colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
University of Bari "A. Moro

Curated by ChEMBL
LigandPNGBDBM50084649(CHEMBL3114664)
Affinity DataIC50:  580nMAssay Description:Inhibition of COX1 in human OVCAR3 cells using [14C]arachidonic acid as substrate preincubated for 30 mins before substrate addition by radioactivity...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Universit£

Curated by ChEMBL
LigandPNGBDBM50084649(CHEMBL3114664)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of ovine COX1 by peroxidase activity-based colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed