BDBM50084649 CHEMBL3114664
SMILES Nc1onc(-c2ccc(Cl)o2)c1-c1ccccc1
InChI Key InChIKey=ABPABQXEIYHSAF-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50084649
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of ovine COX-1 assessed as inhibition of PGH2 production using arachidonic acid as substrate by TMPD oxidation based colorimetric assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
University of Bari "A. Moro
Curated by ChEMBL
University of Bari "A. Moro
Curated by ChEMBL
Affinity DataIC50: 580nMAssay Description:Inhibition of COX1 in human OVCAR3 cells using [14C]arachidonic acid as substrate preincubated for 30 mins before substrate addition by radioactivity...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of ovine COX1 by peroxidase activity-based colorimetric assayMore data for this Ligand-Target Pair