BDBM50084742 4-(4-Methoxy-benzenesulfonyl)-piperazine-1,3-dicarboxylic acid 1-(benzyl-methyl-amide) 3-hydroxyamide::CHEMBL126004

SMILES COc1ccc(cc1)S(=O)(=O)N1CCN(CC1C(=O)NO)C(=O)N(C)Cc1ccccc1

InChI Key InChIKey=SJJAJPMVTRAZSX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50084742   

TargetCollagenase 3(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084742(4-(4-Methoxy-benzenesulfonyl)-piperazine-1,3-dicar...)
Affinity DataIC50:  1.80nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
University Of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50084742(4-(4-Methoxy-benzenesulfonyl)-piperazine-1,3-dicar...)
Affinity DataIC50:  38nMAssay Description:Binding affinity towards matrix metalloprotease-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084742(4-(4-Methoxy-benzenesulfonyl)-piperazine-1,3-dicar...)
Affinity DataIC50:  322nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
University Of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50084742(4-(4-Methoxy-benzenesulfonyl)-piperazine-1,3-dicar...)
Affinity DataIC50:  38nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed