BDBM50095219 2-(4-Benzyl-piperidine-1-sulfonyl)-N-hydroxy-benzamide::CHEMBL319055

SMILES ONC(=O)c1ccccc1S(=O)(=O)N1CCC(Cc2ccccc2)CC1

InChI Key InChIKey=YTDQNSGULXQVKB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50095219   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50095219(2-(4-Benzyl-piperidine-1-sulfonyl)-N-hydroxy-benza...)
Affinity DataIC50:  148nMAssay Description:50 percent inhibition of human Matrix metalloprotease-2 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50095219(2-(4-Benzyl-piperidine-1-sulfonyl)-N-hydroxy-benza...)
Affinity DataIC50: >1.00E+4nMAssay Description:50 percent inhibition of human Matrix metalloprotease-1 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50095219(2-(4-Benzyl-piperidine-1-sulfonyl)-N-hydroxy-benza...)
Affinity DataIC50:  1.00E+3nMAssay Description:50 percent inhibition of human Matrix metalloprotease-13 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed