BDBM50096675 3-(1-Benzyloxy-3-cyclopropyl-1-trifluoromethyl-prop-2-ynyl)-1H-pyridin-2-one::CHEMBL320282

SMILES FC(F)(F)C(OCc1ccccc1)(C#CC1CC1)c1ccc[nH]c1=O

InChI Key InChIKey=MCOWTFYQFKENOA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50096675   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50096675(3-(1-Benzyloxy-3-cyclopropyl-1-trifluoromethyl-pro...)
Affinity DataIC50:  12nMAssay Description:Inhibition of the NNRTI HIV-1 enzyme by 50% using enzyme assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed