BDBM50096792 CHEMBL3580759

SMILES CN1CCN(CC1)C(=O)C[C@H](NC(=O)\C=C\c1cc(Cl)ccc1-n1cnnn1)c1nc(c(Cl)[nH]1)-c1ccc2[nH]c(=O)cc(O)c2c1

InChI Key InChIKey=QURJCLPLOGZUQW-ZIMJUVOESA-N

Data  13 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50096792   

TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50096792(CHEMBL3580759)
Affinity DataKi:  0.0400nMAssay Description:Inhibition of human coagulation factor 11a using p-nitroaniline as substrate assessed as substrate hydrolysis by spectrophotometryMore data for this Ligand-Target Pair
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50096792(CHEMBL3580759)
Affinity DataKi:  0.100nMAssay Description:Inhibition of human coagulation factor 11a using p-nitroaniline as substrate assessed as substrate hydrolysis at 37 degC by spectrophotometryMore data for this Ligand-Target Pair
TargetPlasma kallikrein(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50096792(CHEMBL3580759)
Affinity DataKi:  7nMAssay Description:Inhibition of plasma kallikrein (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50096792(CHEMBL3580759)
Affinity DataKi: >1.60E+3nMAssay Description:Inhibition of urokinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50096792(CHEMBL3580759)
Affinity DataKi:  6.20E+3nMAssay Description:Inhibition of trypsin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50096792(CHEMBL3580759)
Affinity DataKi:  7.40E+3nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50096792(CHEMBL3580759)
Affinity DataKi: >9.00E+3nMAssay Description:Inhibition of coagulation factor 10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50096792(CHEMBL3580759)
Affinity DataKi: >1.33E+4nMAssay Description:Inhibition of coagulation factor 7a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50096792(CHEMBL3580759)
Affinity DataKi: >2.00E+4nMAssay Description:Inhibition of coagulation factor 12a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50096792(CHEMBL3580759)
Affinity DataKi:  2.90E+4nMAssay Description:Inhibition of tPA (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50096792(CHEMBL3580759)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of tissue kallikrein (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50096792(CHEMBL3580759)
Affinity DataKi: >5.40E+4nMAssay Description:Inhibition of APC (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50096792(CHEMBL3580759)
Affinity DataKi: >6.00E+4nMAssay Description:Inhibition of coagulation factor 9a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed