BDBM50097941 4-(4-Amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-phenol::4-(4-amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)phenol::CHEMBL169570

SMILES Nc1ncnc2n(cc(-c3ccc(O)cc3)c12)C1CCCC1

InChI Key InChIKey=PXGNDOOTUBVRMA-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50097941   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Novartis Pharma Research

Curated by ChEMBL
LigandPNGBDBM50097941(4-(4-Amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidi...)
Affinity DataIC50:  250nMAssay Description:Inhibition of Epidermal growth factor receptor (EGF-R) tyrosine kinase activity More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Gallus gallus (Chicken))
Novartis Pharma Research

Curated by ChEMBL
LigandPNGBDBM50097941(4-(4-Amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidi...)
Affinity DataIC50:  300nMAssay Description:Inhibition of p60 c-Src tyrosine kinase mediated phosphorylation of Fak in IC8.1 fibroblastsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Novartis Pharma Research

Curated by ChEMBL
LigandPNGBDBM50097941(4-(4-Amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidi...)
Affinity DataIC50:  110nMAssay Description:Inhibition of v-Abl tyrosine kinase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Gallus gallus (Chicken))
Novartis Pharma Research

Curated by ChEMBL
LigandPNGBDBM50097941(4-(4-Amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidi...)
Affinity DataIC50:  20nMAssay Description:Inhibition of p60 c-Src tyrosine kinase mediated phosphorylation of Fak in IC8.1 fibroblastsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50097941(4-(4-Amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidi...)
Affinity DataIC50:  19.9nMAssay Description:Inhibition of c-SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed