BDBM50099293 3N-{4-[4-(4-chlorophenyl)-1-methyl-(3R,4S)-hexahydro-3-pyridinylcarboxamido]butyl}-4-(4-chlorophenyl)-1-methyl-(3R,4S)-hexahydro-3-pyridinecarboxamide::CHEMBL44046

SMILES CN1CC[C@@H]([C@H](C1)C(=O)NCCCCNC(=O)[C@H]1CN(C)CC[C@@H]1c1ccc(Cl)cc1)c1ccc(Cl)cc1

InChI Key InChIKey=QJTIBSMGWLVSTE-VIJSPRBVSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50099293   

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50099293(3N-{4-[4-(4-chlorophenyl)-1-methyl-(3R,4S)-hexahyd...)
Affinity DataKi:  33nMAssay Description:Inhibition of high affinity DA uptake into rat synaptosomes using [3H]DAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50099293(3N-{4-[4-(4-chlorophenyl)-1-methyl-(3R,4S)-hexahyd...)
Affinity DataKi:  81nMAssay Description:Displacement of [3H]mazindol binding to dopamine transporter (DAT) in rat synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50099293(3N-{4-[4-(4-chlorophenyl)-1-methyl-(3R,4S)-hexahyd...)
Affinity DataKi:  104nMAssay Description:Ability to inhibit high affinity uptake of norepinephrine transporter into the nerve endings of rat synaptosomes using [3H]NE as a radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50099293(3N-{4-[4-(4-chlorophenyl)-1-methyl-(3R,4S)-hexahyd...)
Affinity DataKi:  534nMAssay Description:Inhibition of high affinity serotonin uptake into rat synaptosomes using [3H]5-HTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed