BDBM50099870 CHEMBL29022::Sodium; (E)-2-amino-5-biphenyl-2-yl-5-(2,4-difluoro-phenyl)-pent-4-enoate

SMILES NC(C\C=C(\c1ccc(F)cc1F)c1ccccc1-c1ccccc1)C([O-])=O

InChI Key InChIKey=MELCIKNELJLXGI-XDHOZWIPSA-M

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50099870   

TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099870(CHEMBL29022 | Sodium; (E)-2-amino-5-biphenyl-2-yl-...)
Affinity DataIC50:  2.75E+3nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099870(CHEMBL29022 | Sodium; (E)-2-amino-5-biphenyl-2-yl-...)
Affinity DataIC50:  8.92E+3nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-1 isoform C (GlyT-1c) transporter cells after incubation at 30 degrees...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed