BDBM50101767 3-Benzo[1,3]dioxol-5-yl-3-{[5-((E)-3-guanidino-3-oxo-propenyl)-thiophene-2-carbonyl]-amino}-propionic acid::CHEMBL61469

SMILES OC(=O)CC(NC(=O)c1ccc(\C=C\C(=O)NC2=NCCCN2)s1)c1ccc2OCOc2c1

InChI Key InChIKey=BFNUKIPKFIGXEA-QPJJXVBHSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50101767   

TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50101767(3-Benzo[1,3]dioxol-5-yl-3-{[5-((E)-3-guanidino-3-o...)
Affinity DataIC50:  4.10E+4nMAssay Description:Concentration required to reduce binding of human 293 cell attachment to immobilized vitronectin receptor(Vn/293) by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50101767(3-Benzo[1,3]dioxol-5-yl-3-{[5-((E)-3-guanidino-3-o...)
Affinity DataIC50: >1.00E+4nMAssay Description:Concentration required to reduce binding of fibrinogen (Fg) to alpha IIb beta3 integrin by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50101767(3-Benzo[1,3]dioxol-5-yl-3-{[5-((E)-3-guanidino-3-o...)
Affinity DataIC50:  8nMAssay Description:Concentration required to reduce binding of human 293 cell attachment to immobilized vitronectin receptor(Vn/293) by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed