BDBM50113629 CHEMBL3604632

SMILES CC(C)Oc1cc(C2CCN(C)CC2)c(C)cc1Nc1ncc(Cl)c(Nc2cn(C)nc2S(=O)(=O)C(C)C)n1

InChI Key InChIKey=CNIWZQPSVDYFSY-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50113629   

TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Beijing Pearl Biotech

Curated by ChEMBL
LigandPNGBDBM50113629(CHEMBL3604632)
Affinity DataIC50:  4nMAssay Description:Inhibition of wild type human recombinant ALK using TK substrate-biotin incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Beijing Pearl Biotech

Curated by ChEMBL
LigandPNGBDBM50113629(CHEMBL3604632)
Affinity DataIC50:  8nMAssay Description:Inhibition of ALK L1196M mutant (unknown origin) using TK substrate-biotin incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair