BDBM50114395 CHEMBL3605564

SMILES CC(=O)OC[C@]12CC[C@H]3[C@@H](CC=C4CC=CC(=O)[C@@]43C)[C@]1(O)CC[C@@]2(O)[C@@](C)(O)[C@H]1CC(C)=C(C)C(=O)O1

InChI Key InChIKey=RGHQRULWHKEQHE-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50114395   

TargetBromodomain-containing protein 3(Human)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50114395BDBM50114395(CHEMBL3605564)
Affinity DataIC50: 18nMAssay Description:Inhibition of BRD3-BD1 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50114395BDBM50114395(CHEMBL3605564)
Affinity DataIC50: 19nMAssay Description:Inhibition of BRD4-BD1 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetAndrogen receptor(Human)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50114395BDBM50114395(CHEMBL3605564)
Affinity DataIC50: 580nMAssay Description:Inhibition of androgen receptor in human LNCAP cells assessed as inhibition of DHT-induced KLK2 gene expression by Array Plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50114395BDBM50114395(CHEMBL3605564)
Affinity DataIC50: 750nMAssay Description:Inhibition of androgen receptor in human LNCAP cells assessed as inhibition of DHT-induced KLK3 gene expression by Array Plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50114395BDBM50114395(CHEMBL3605564)
Affinity DataIC50: 770nMAssay Description:Inhibition of androgen receptor in human LNCAP cells assessed as inhibition of DHT-induced SPDEF gene expression by Array Plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50114395BDBM50114395(CHEMBL3605564)
Affinity DataIC50: 3.92E+3nMAssay Description:Inhibition of BRD4-BD2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetBromodomain-containing protein 3(Human)
University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50114395BDBM50114395(CHEMBL3605564)
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of BRD3-BD2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed