BDBM50117787 CHEMBL89750::[{2-[2-(4-Fluoro-benzylsulfanyl)-5-(1-methyl-1H-pyrazol-4-ylmethyl)-4-oxo-4H-pyrimidin-1-yl]-acetyl}-(4'-trifluoromethyl-biphenyl-4-ylmethyl)-amino]-acetic acid

SMILES Cn1cc(Cc2cn(CC(=O)N(CC(O)=O)Cc3ccc(cc3)-c3ccc(cc3)C(F)(F)F)c(SCc3ccc(F)cc3)nc2=O)cn1

InChI Key InChIKey=SBMHFUHIBLNLAR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50117787   

TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50117787(CHEMBL89750 | [{2-[2-(4-Fluoro-benzylsulfanyl)-5-(...)
Affinity DataIC50:  3.10E+4nMAssay Description:Inhibition of cytochrome P450 3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50117787(CHEMBL89750 | [{2-[2-(4-Fluoro-benzylsulfanyl)-5-(...)
Affinity DataIC50:  1nMAssay Description:Inhibitory concentration against Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) was estimatedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed