BDBM50120274 3-(2,4-Dioxo-3,4,5,6,7,8-hexahydro-2H-quinazolin-1-yl)-N-(2-naphthalen-2-yl-2-oxo-ethyl)-propionamide::CHEMBL432211

SMILES O=C(CCn1c2CCCCc2c(=O)[nH]c1=O)NCC(=O)c1ccc2ccccc2c1

InChI Key InChIKey=CKBYPHXZBYAHFP-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50120274   

TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50120274(3-(2,4-Dioxo-3,4,5,6,7,8-hexahydro-2H-quinazolin-1...)
Affinity DataEC50:  800nMAssay Description:Concentration required to inhibit human recombinant PARP-1 was determined using cell protection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50120274(3-(2,4-Dioxo-3,4,5,6,7,8-hexahydro-2H-quinazolin-1...)
Affinity DataIC50:  25nMAssay Description:Inhibitory activity against human recombinant PARP-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed