BDBM50120471 CHEMBL148054::ethyl 2-[1'-benzylspiro[1,3-dihydroisobenzofuran-1,4'-(hexahydropyridine)]-3-yl]acetate

SMILES CCOC(=O)CC1OC2(CCN(Cc3ccccc3)CC2)c2ccccc12

InChI Key InChIKey=UGHBJNQFYIFUDZ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50120471   

TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Pharmazeutisches Institut Der Universit£T Freiburg

Curated by ChEMBL
LigandPNGBDBM50120471(CHEMBL148054 | ethyl 2-[1'-benzylspiro[1,3-dihydro...)
Affinity DataKi:  15.1nMAssay Description:Ability to displace [3H](+)-pentazocine from Sigma opioid receptor type 1 of guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Pharmazeutisches Institut Der Universit£T Freiburg

Curated by ChEMBL
LigandPNGBDBM50120471(CHEMBL148054 | ethyl 2-[1'-benzylspiro[1,3-dihydro...)
Affinity DataKi:  6.77E+3nMAssay Description:Ability to displace [3H]ditolylguanidine in the presence of 100 nM (+)-pentazocine from Sigma opioid receptor type 2 of rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed