BDBM50124010 2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-methyl-butyl)-3-methyl-butyramide::CHEMBL168471

SMILES CC(C)C[C@@H](NC(=O)[C@@H](NS(=O)(=O)c1ccc(F)cc1)C(C)C)C=O

InChI Key InChIKey=WSJWUIDLGZAXID-ZBFHGGJFSA-N

Data  15 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50124010   

TargetCytochrome P450 2C9(Homo sapiens (Human))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50:  4.92E+5nMAssay Description:Inhibition of Cytochrome P450 2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Rattus norvegicus)
University Of Canterbury

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of rat CAPN1 using BODIPY-labeled casein substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibitory activity against ChymotrypsinogenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50:  78nMAssay Description:Inhibitory activity against Cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50: >6.00E+4nMAssay Description:Inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50:  1.00E+6nMAssay Description:Inhibition of Cytochrome P450 1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50:  8.10E+4nMAssay Description:Inhibition of Cytochrome P450 3A4 as BFC substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50:  5.31E+5nMAssay Description:Inhibition of Cytochrome P450 3A4 as BQ substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against interleukin 1beta converting enzyme (IL-1 beta converting enzyme)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against coagulation factor VIIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50:  1.77E+5nMAssay Description:Inhibition of Cytochrome P450 2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50:  2.91E+5nMAssay Description:Inhibition of Cytochrome P450 2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50:  7.5nMAssay Description:In vitro inhibition of porcine mu-calpain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed