BDBM50125902 (1S,4R)-4-(2-Benzhydryloxy-ethyl)-1-(4-fluoro-benzyl)-piperidin-3-ol::CHEMBL21213

SMILES OC1CN(Cc2ccc(F)cc2)CC[C@@H]1CCOC(c1ccccc1)c1ccccc1

InChI Key InChIKey=SEGLRXUOVKIQDG-FPSALIRRSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50125902   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50125902((1S,4R)-4-(2-Benzhydryloxy-ethyl)-1-(4-fluoro-benz...)
Affinity DataIC50:  3.60E+3nMAssay Description:Binding affinity towards serotonin transporter in rat striatum using [3H]citalopram as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50125902((1S,4R)-4-(2-Benzhydryloxy-ethyl)-1-(4-fluoro-benz...)
Affinity DataIC50:  4.05nMAssay Description:Inhibition of uptake from dopamine transporter in rat striatum using [3H]DA as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50125902((1S,4R)-4-(2-Benzhydryloxy-ethyl)-1-(4-fluoro-benz...)
Affinity DataIC50:  1.88E+3nMAssay Description:Binding affinity towards norepinephrine transporter in rat striatum using [3H]nisoxetine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50125902((1S,4R)-4-(2-Benzhydryloxy-ethyl)-1-(4-fluoro-benz...)
Affinity DataIC50:  0.460nMAssay Description:Binding affinity towards dopamine transporter in rat striatum using [3H]WIN-35 428 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed