BDBM50139570 4-(5-{[2-(3,5-Difluoro-benzyl)-3-oxo-2,3,4,5-tetrahydro-1H-benzo[c]azepin-4-ylamino]-methyl}-imidazol-1-ylmethyl)-benzonitrile::CHEMBL350736

SMILES Fc1cc(F)cc(CN2Cc3ccccc3CC(NCc3cncn3Cc3ccc(cc3)C#N)C2=O)c1

InChI Key InChIKey=TWNBGUAWTJEEOF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50139570   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50139570(4-(5-{[2-(3,5-Difluoro-benzyl)-3-oxo-2,3,4,5-tetra...)
Affinity DataIC50:  8nMAssay Description:Inhibition of farnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed