BDBM50139758 (2-Naphthalen-2-yl-1-naphthalen-1-yl-2-oxo-ethyl)-phosphonic acid::1-(naphthalen-1-yl)-2-(naphthalen-2-yl)-2-oxoethylphosphonic acid::CHEMBL424224
SMILES OP(O)(=O)C(C(=O)c1ccc2ccccc2c1)c1cccc2ccccc12
InChI Key InChIKey=OFHMUASCSJJNNA-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50139758
Affinity DataKi: 2.30nMAssay Description:Inhibition of chymase in human mast cells using Suc-Ala-Ala-Pro-Phe-(p-nitroanilide) as substrate for 15 mins by spectrophotometric methodMore data for this Ligand-Target Pair
TargetCathepsin G(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibitory activity of the compound against human Cathepsin GMore data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:Tested for 50% of inhibition of Osteoclastic acid phosphatase (OAP) activity, determined using dose-response curveMore data for this Ligand-Target Pair