BDBM50144845 (S)-2-(6-Chloro-5-fluoro-2,3-dihydro-indol-1-yl)-1-methyl-ethylamine::CHEMBL80366

SMILES C[C@H](N)CN1CCc2cc(F)c(Cl)cc12

InChI Key InChIKey=OKTLNQVSINRJKA-UHFFFAOYSA-N

Data  3 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50144845   

Target5-hydroxytryptamine receptor 2B(Human)
Vernalis Research

Curated by ChEMBL
LigandPNGBDBM50144845((S)-2-(6-Chloro-5-fluoro-2,3-dihydro-indol-1-yl)-1...)
Affinity DataEC50:  7.30nMAssay Description:Functional activity against human 5-hydroxytryptamine 2B receptor expressed in CHO cells using fluorometric imaging plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Vernalis Research

Curated by ChEMBL
LigandPNGBDBM50144845((S)-2-(6-Chloro-5-fluoro-2,3-dihydro-indol-1-yl)-1...)
Affinity DataEC50:  31nMAssay Description:Affinity for human 5-hydroxytryptamine 2C receptor expressed in mammalian cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Vernalis Research

Curated by ChEMBL
LigandPNGBDBM50144845((S)-2-(6-Chloro-5-fluoro-2,3-dihydro-indol-1-yl)-1...)
Affinity DataEC50:  367nMAssay Description:Functional activity against human 5-hydroxytryptamine 2A receptor expressed in CHO cells using fluorometric imaging plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Vernalis Research

Curated by ChEMBL
LigandPNGBDBM50144845((S)-2-(6-Chloro-5-fluoro-2,3-dihydro-indol-1-yl)-1...)
Affinity DataKi:  14nMAssay Description:Affinity for human 5-hydroxytryptamine 2C receptor expressed in mammalian cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Vernalis Research

Curated by ChEMBL
LigandPNGBDBM50144845((S)-2-(6-Chloro-5-fluoro-2,3-dihydro-indol-1-yl)-1...)
Affinity DataKi:  31nMAssay Description:Affinity for human 5-hydroxytryptamine 2B receptor expressed in mammalian cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Vernalis Research

Curated by ChEMBL
LigandPNGBDBM50144845((S)-2-(6-Chloro-5-fluoro-2,3-dihydro-indol-1-yl)-1...)
Affinity DataKi:  167nMAssay Description:Affinity for human 5-hydroxytryptamine 2A receptor expressed in mammalian cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed