BDBM50145863 CHEMBL3764185

SMILES Cc1c(N[C@@H]2CCC[C@@]2(C)O)ccc(C#N)c1Cl

InChI Key InChIKey=CXFSVKGROITHRY-TZMCWYRMSA-N

Data  4 KI  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50145863   

TargetAndrogen receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50145863(CHEMBL3764185)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]-methyltrienolone from androgen receptor (unknown origin) expressed in HEK293 cell lysate incubated overnight by microbeta scinti...More data for this Ligand-Target Pair
TargetProgesterone receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50145863(CHEMBL3764185)
Affinity DataKi:  872nMAssay Description:Displacement of [3H]-methyltrienolone from progesterone receptor (unknown origin) expressed in HEK293 cell lysate incubated overnight by microbeta sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50145863(CHEMBL3764185)
Affinity DataKi:  1.45E+3nMAssay Description:Displacement of [3H]-aldosterone from mineralocorticoid receptor (unknown origin) expressed in HEK293 cell lysate incubated overnight by microbeta sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50145863(CHEMBL3764185)
Affinity DataKi: >6.02E+3nMAssay Description:Displacement of [3H]-dexamethasone from glucocorticoid receptor (unknown origin) expressed in HEK293 cell lysate incubated overnight by microbeta sci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50145863(CHEMBL3764185)
Affinity DataEC50:  0.499nMAssay Description:Agonist activity at human androgen receptor expressed in mouse C2C12 cells cotransfected with GRE/ARE reporter plasmid assessed as receptor transacti...More data for this Ligand-Target Pair