BDBM50152162 CHEMBL188844::CHEMBL2165204::[3-(6-Dimethylamino-pyridin-3-yl)-2,5-dimethyl-pyrazolo[1,5-a]pyrimidin-7-yl]-dipropyl-amine

SMILES CCCN(CCC)c1cc(C)nc2c(c(C)nn12)-c1ccc(nc1)N(C)C

InChI Key InChIKey=QJEURMFEYXHROW-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50152162   

TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50152162(CHEMBL188844 | CHEMBL2165204 | [3-(6-Dimethylamino...)
Affinity DataKi:  1.70nMAssay Description:Binding affinity to CRFR1 by autoradiographyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50152162(CHEMBL188844 | CHEMBL2165204 | [3-(6-Dimethylamino...)
Affinity DataKi:  4.20nMAssay Description:Inhibition of [125I]-o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50152162(CHEMBL188844 | CHEMBL2165204 | [3-(6-Dimethylamino...)
Affinity DataIC50:  110nMAssay Description:Inhibition of [125I]-o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed