BDBM50153135 1-[1-(3,3-Diphenyl-propyl)-piperidin-4-yl]-3,4-dihydro-1H-benzo[1,2,6]thiadiazine 2,2-dioxide::CHEMBL362160

SMILES O=S1(=O)NCc2ccccc2N1C1CCN(CCC(c2ccccc2)c2ccccc2)CC1

InChI Key InChIKey=NDZSAXNYUWXFLL-UHFFFAOYSA-N

Data  4 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50153135   

TargetMu-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153135(1-[1-(3,3-Diphenyl-propyl)-piperidin-4-yl]-3,4-dih...)
Affinity DataKi:  13nMAssay Description:Inhibition of [3H]diprenorphine binding to human Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153135(1-[1-(3,3-Diphenyl-propyl)-piperidin-4-yl]-3,4-dih...)
Affinity DataKi:  83nMAssay Description:Inhibition of [3H]nociceptin binding to human Opioid receptor like 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153135(1-[1-(3,3-Diphenyl-propyl)-piperidin-4-yl]-3,4-dih...)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of [3H]U-69593 binding to human Opioid receptor kappa 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153135(1-[1-(3,3-Diphenyl-propyl)-piperidin-4-yl]-3,4-dih...)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of [3H]naltrindole binding to human Opioid receptor delta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153135(1-[1-(3,3-Diphenyl-propyl)-piperidin-4-yl]-3,4-dih...)
Affinity DataEC50:  1.65E+3nMAssay Description:Agonist activity as stimulation of [35S]-GTP-gamma binding to human Opioid receptor like 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153135(1-[1-(3,3-Diphenyl-propyl)-piperidin-4-yl]-3,4-dih...)
Affinity DataEC50:  801nMAssay Description:Agonist activity as stimulation of [35S]-GTP-gamma binding to human Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed