BDBM50154449 5-[4-(2-Amino-ethylamino)-3-nitro-phenyl]-6-ethyl-pyrimidine-2,4-diamine::CHEMBL84440::NCI-372939::cid_3449946

SMILES CCc1nc(N)nc(N)c1-c1ccc(NCCN)c(c1)[N+]([O-])=O

InChI Key InChIKey=XYSUDZRZSXTBRQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50154449   

TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50154449(5-[4-(2-Amino-ethylamino)-3-nitro-phenyl]-6-ethyl-...)
Affinity DataIC50:  5.66E+3nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Leicester

Curated by ChEMBL
LigandPNGBDBM50154449(5-[4-(2-Amino-ethylamino)-3-nitro-phenyl]-6-ethyl-...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50154449(5-[4-(2-Amino-ethylamino)-3-nitro-phenyl]-6-ethyl-...)
Affinity DataIC50: >8.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50154449(5-[4-(2-Amino-ethylamino)-3-nitro-phenyl]-6-ethyl-...)
Affinity DataIC50:  6.08E+3nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay