BDBM50157253 5-[(4-Fluoro-3-trifluoromethyl-benzyloxy)-(3-methyl-3H-imidazol-4-yl)-methyl]-2''-trifluoromethyl-biphenyl-2-carbonitrile::CHEMBL361357
SMILES Cn1cncc1C(OCc1ccc(F)c(c1)C(F)(F)F)c1ccc(C#N)c(c1)-c1ccccc1C(F)(F)F
InChI Key InChIKey=BLJYZDNOIAHURN-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50157253
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 4.10nMAssay Description:Inhibition of Bovine farnesyl transeferaseMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Mus musculus)
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataEC50: 100nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
TargetGeranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of Bovine Geranyl geranyl transeferaseMore data for this Ligand-Target Pair