BDBM50158453 CHEMBL224400::N-(3-Phenylamino-4-pyridinyl)trifluoromethanesulfonamide

SMILES FC(F)(F)S(=O)(=O)Nc1ccncc1Nc1ccccc1

InChI Key InChIKey=JLNFQYSZNBKQDV-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50158453   

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158453(CHEMBL224400 | N-(3-Phenylamino-4-pyridinyl)triflu...)
Affinity DataIC50:  180nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of calcium ionophore A-23187-stimulated platelet aggregation by measuring TXB2 product...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158453(CHEMBL224400 | N-(3-Phenylamino-4-pyridinyl)triflu...)
Affinity DataIC50:  90nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158453(CHEMBL224400 | N-(3-Phenylamino-4-pyridinyl)triflu...)
Affinity DataIC50:  180nMAssay Description:Inhibition of COX1 in human whole blood assessed as TXB2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158453(CHEMBL224400 | N-(3-Phenylamino-4-pyridinyl)triflu...)
Affinity DataIC50:  90nMAssay Description:Inhibition of COX2 in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158453(CHEMBL224400 | N-(3-Phenylamino-4-pyridinyl)triflu...)
Affinity DataIC50:  90nMAssay Description:Inhibition of COX2 in LPS-stimulated human whole blood assessed as PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50158453(CHEMBL224400 | N-(3-Phenylamino-4-pyridinyl)triflu...)
Affinity DataIC50:  180nMAssay Description:Inhibition of COX1 in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed