BDBM50165345 CHEMBL3800317

SMILES COc1ccc(\C=C\C(=O)OCC(=O)Nc2c3CCCCc3nc3ccccc23)cc1OC

InChI Key InChIKey=ZETLFYVRVQQPJA-WYMLVPIESA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50165345   

TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50165345(CHEMBL3800317)
Affinity DataIC50:  49nMAssay Description:Inhibition of self-mediated amyloid beta (1 to 42) (unknown origin) aggregation after 24 hrs by thioflavin T fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50165345(CHEMBL3800317)
Affinity DataIC50:  159nMAssay Description:Inhibition of equine serum BuChE using butylthiocholine chloride as substrate preincubated for 20 mins followed by substrate addition by Ellman's met...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50165345(CHEMBL3800317)
Affinity DataIC50:  16nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine chloride as substrate preincubated for 20 mins followed by substrate addition by Ellman's met...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed