BDBM50174285 3-(4-pentylbicyclo[2.2.2]octan-1-yl)-5,6,7,8,9,10-hexahydro-[1,2,4]triazolo[4,3-a]azocine::CHEMBL200513
SMILES CCCCCC12CCC(CC1)(CC2)c1nnc2CCCCCCn12
InChI Key InChIKey=HISKJZZJMYSEGO-UHFFFAOYSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50174285
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against mouse 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibitory activity against mouse 11beta-HSD2More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against human 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]-cortisone to [3H]-cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of human 11beta-HSD2 expressed in CHO-K1 cells assessed as conversion of [3H]-cortisol to [3H]-cortisone by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of mouse 11beta-HSD2 expressed in CHO-K1 cells assessed as conversion of [3H]-cortisol to [3H]-cortisone by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]-cortisone to [3H]-cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 183nMAssay Description:Inhibitory activity against human 11beta-HSD2More data for this Ligand-Target Pair