BDBM50182705 4-chloro-6-(4-(4-ethylpiperazin-1-yl)-1H-pyrazol-3-yl)benzene-1,3-diol::CHEMBL426848

SMILES CCN1CCN(CC1)c1c[nH]nc1-c1cc(Cl)c(O)cc1O

InChI Key InChIKey=HQCGDXONSJOHBF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50182705   

TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Vernalis

Curated by ChEMBL
LigandPNGBDBM50182705(4-chloro-6-(4-(4-ethylpiperazin-1-yl)-1H-pyrazol-3...)
Affinity DataIC50:  1.17E+4nMAssay Description:Inhibition of HSP90 ATPase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Vernalis

Curated by ChEMBL
LigandPNGBDBM50182705(4-chloro-6-(4-(4-ethylpiperazin-1-yl)-1H-pyrazol-3...)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of HSP90 by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed