BDBM50191492 CHEMBL3919183

SMILES CCC(=O)Nc1cc2c(Nc3ccc4n(Cc5ccccn5)ncc4c3)ncnc2cc1OC

InChI Key InChIKey=KABLMFMHWJFKIW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50191492   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50191492(CHEMBL3919183)
Affinity DataIC50:  94nMAssay Description:Irreversible inhibition of GST-tagged ERBB1 (unknown origin) (Met-668 to Ala-1211 residues) expressed in baculovirus infected Sf9 insect cells assess...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50191492(CHEMBL3919183)
Affinity DataIC50:  15nMAssay Description:Irreversible inhibition of GST-tagged ERBB4 (unknown origin) (Gly-259 to Gly-690 residues) expressed in baculovirus infected Sf9 insect cells assesse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed