BDBM50192579 (R)-4-(2-oxo-1,2-dihydropyrido[3,4-d]pyrimidin-3(4H)-yl)-N-(2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)piperidine-1-carboxamide::CHEMBL427743

SMILES FC(F)(F)CN1c2ccccc2C(=N[C@@H](NC(=O)N2CCC(CC2)N2Cc3ccncc3NC2=O)C1=O)c1ccccc1

InChI Key InChIKey=VVNUSRVWEZRZFD-SANMLTNESA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50192579   

TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192579((R)-4-(2-oxo-1,2-dihydropyrido[3,4-d]pyrimidin-3(4...)
Affinity DataKi:  350nMAssay Description:Displacement of [125I]CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192579((R)-4-(2-oxo-1,2-dihydropyrido[3,4-d]pyrimidin-3(4...)
Affinity DataIC50:  224nMAssay Description:Activity at CGRP receptor assessed as inhibition of CGRP-stimulated cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed